beta-thalassemia


beta-thalassemia
β-талассемия, анемия Кули
НЗЧ, форма гемолитической анемии hemolytic anemia, обусловленное мутациями гена бета-гемоглобина (различного типа - например, приводящие к образованию гемоглобина Лепора hemoglobin Lepore или гемоглобина Кения (Kenya hemoglobin), мутации в области промотора и т.п.); при -Т. увеличено содержание фетального гемоглобина fetal hemoglobin, мутации могут ослаблять синтез -гемоглобина (+-талассемия) или полностью его блокировать (0-талассемия); относительно более широкое распространение -Т. в тропиках связано с тем, что больные имеют преимущества в связи с устойчивостью к малярии.

Англо-русский толковый словарь генетических терминов. — М.: Изд-во ВНИРО. . 1995.

Смотреть что такое "beta-thalassemia" в других словарях:

  • Beta-thalassemia — Classification and external resources ICD 10 D56.1 ICD 9 282.44 …   Wikipedia

  • beta-thalassemia — be·ta thal·as·se·mia or ß thalassemia or Brit be·ta thal·as·sae·mia or ß thalassaemia .thal ə sē mē ə n thalassemia in which the hemoglobin chain designated beta is affected and which comprises Cooley s anemia in the homozygous condition and… …   Medical dictionary

  • beta-thalassemia — ˈ ̷ ̷  ̷ ̷ ˌ ̷ ̷  ̷ ̷ ˈ ̷ ̷  ̷ ̷  ̷ ̷ noun : thalassemia in which the hemoglobin chain designated beta is affected and which comprises Cooley s anemia in the homozygous condition and a thalassemia minor in the heterozygous condition …   Useful english dictionary

  • beta-thalassemia — noun Date: 1962 thalassemia in which the longer hemoglobin chain is affected and which comprises Cooley s anemia in the homozygous condition and thalassemia minor in the heterozygous condition …   New Collegiate Dictionary

  • Thalassemia — Classification and external resources ICD 10 D56 ICD 9 282.4 …   Wikipedia

  • beta globin — also ß glo·bin glō bən n the chain of hemoglobin that is designated beta and that when deficient or defective causes various anemias (as beta thalassemia or sickle cell anemia) …   Medical dictionary

  • Thalassemia major — The dire disease also known as beta thalassemia. The clinical picture of this form of anemia was first described in 1925 by the pediatrician Thomas Benton Cooley. Other names for the disease are Cooley’s anemia and Mediterranean anemia. The… …   Medical dictionary

  • Thalassemia, beta — Also known as thalassemia major .The clinical picture of this important type of anemia was first described in 1925 by the pediatrician Thomas Benton Cooley.. Other names for the disease are Cooley’s anemia and Mediterranean anemia. The name… …   Medical dictionary

  • Thalassemia, alpha — A blood disorder, thalassemia is not one disease but rather a group of disorders that have a single feature in common: they all have a genetic defect in the production of hemoglobin, the protein that enables red blood cells to carry oxygen. All… …   Medical dictionary

  • Thalassemia minor — Also called thalassemia trait, thalassemia minor is the carrier state for beta thalassemia. People who are carriers (heterozygotes) have just one thalassemia gene, are said to have thalassemia minor, and are essentially normal * * * thalassemia… …   Medical dictionary

  • Thalassemia — Not just one disease but rather a complex series of genetic (inherited) disorders all of which involve underproduction of hemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of hemoglobin is made up of 4 …   Medical dictionary


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